TY - JOUR
T1 - Outcomes, Trends, and Healthcare Disparities in Patients Hospitalized with Chronic Limb-Threatening Ischemia
AU - Torres, Christian
AU - Ujueta, Francisco
AU - Rogers, Everett
AU - Ghazzal, Amre
AU - Santos, Radleigh
AU - Koelbl, Christian
AU - Escolar, Esteban
AU - Lamas, Gervasio A.
AU - Parikh, Sahil A.
AU - Beohar, Nirat
PY - 2023/1
Y1 - 2023/1
N2 - BACKGROUND: Chronic limb-threatening ischemia (CLTI) is the most severe form of peripheral artery disease (PAD) and is associated with poor patient outcomes and increased healthcare costs. While racial, socioeconomic, and other healthcare disparities are widely recognized to influence the management of CLTI, the extent of the role they play is still an area of intense investigation. METHODS: We analyzed data from the National Inpatient Sample (NIS) to identify all patients ≥18 years of age admitted with a primary diagnosis of CLTI from 2016 to 2019. Descriptive statistics were used to summarize patient baseline characteristics (age, gender, race, comorbidities, socioeconomic status, and procedural rates). Logistic regression models and temporal trends were used to determine predictors of major amputation and major adverse cardiovascular events (MACE), as well as in CLTI admissions during the 4-year study period, major amputation, endovascular intervention, and peripheral bypass further divided into racial cohorts. RESULTS: A total of 121,087,650 patients were hospitalized from 2016 to 2019 of which 4,707,657 (3.9%) were hospitalized for CLTI. The mean age of patients admitted with CLTI was 60 ± 17 years. A majority were male (57.8%, P
AB - BACKGROUND: Chronic limb-threatening ischemia (CLTI) is the most severe form of peripheral artery disease (PAD) and is associated with poor patient outcomes and increased healthcare costs. While racial, socioeconomic, and other healthcare disparities are widely recognized to influence the management of CLTI, the extent of the role they play is still an area of intense investigation. METHODS: We analyzed data from the National Inpatient Sample (NIS) to identify all patients ≥18 years of age admitted with a primary diagnosis of CLTI from 2016 to 2019. Descriptive statistics were used to summarize patient baseline characteristics (age, gender, race, comorbidities, socioeconomic status, and procedural rates). Logistic regression models and temporal trends were used to determine predictors of major amputation and major adverse cardiovascular events (MACE), as well as in CLTI admissions during the 4-year study period, major amputation, endovascular intervention, and peripheral bypass further divided into racial cohorts. RESULTS: A total of 121,087,650 patients were hospitalized from 2016 to 2019 of which 4,707,657 (3.9%) were hospitalized for CLTI. The mean age of patients admitted with CLTI was 60 ± 17 years. A majority were male (57.8%, P
KW - Chronic limb-threatening ischemia
KW - health disparities
KW - national inpatient sample
KW - peripheral artery disease
UR - https://www.mendeley.com/catalogue/32336a46-eeba-3f11-ad13-628fe078a2de/
U2 - 10.25270/jcli/CLIG23-00019
DO - 10.25270/jcli/CLIG23-00019
M3 - Article
VL - 3
SP - E103-E113
JO - Journal of Critical Limb Ischemia
JF - Journal of Critical Limb Ischemia
IS - 3
ER -